IUBMB Enzyme Nomenclature


Accepted name: fructose 5-dehydrogenase (NADP+)

Reaction: D-fructose + NADP+ = 5-dehydro-D-fructose + NADPH + H+

Other name(s): 5-ketofructose reductase (NADP); 5-keto-D-fructose reductase (NADP+); fructose 5-(nicotinamide adenine dinucleotide phosphate) dehydrogenase; D-(–)fructose:(NADP+) 5-oxidoreductase; fructose 5-dehydrogenase (NADP)

Systematic name: D-fructose:NADP+ 5-oxidoreductase

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, CAS registry number: 37250-53-6


1. Ameyama, M., Matsushita, K., Shinagawa, E. and Adachi, O. 5-keto-D-Fructose reductase of Gluconobacter industrius – Purification, crystallization and properties. Agric. Biol. Chem. 45 (1981) 863-869.

2. Avigad, G., Englard, S. and Pifco, S. 5-keto-D-Fructose. IV. A specific reduced nicotinamide adenine dinucleotide phosphate-linked reductase from Gluconobacter cerinus. J. Biol. Chem. 241 (1966) 373-378. [PMID: 4379259]

[EC created 1972, modified 1976]

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