Reaction: UDP-N-acetyl-D-glucosamine + 2 NAD+ + H2O = UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate + 2 NADH + 2 H+
For diagram of reaction click here.
Other name(s): uridine diphosphoacetylglucosamine dehydrogenase; UDP-acetylglucosamine dehydrogenase; UDP-2-acetamido-2-deoxy-D-glucose:NAD oxidoreductase; UDP-GLcNAc dehydrogenase
Systematic name: UDP-N-acetyl-D-glucosamine:NAD+ 6-oxidoreductase
Links to other databases: BRENDA, EXPASY, KEGG, PDB, CAS registry number: 9054-83-5
References:
1. Fan, D.-F., John, C.E., Zalitis, J. and Feingold, D.S. UDPacetylglucosamine dehydrogenase from Achromobacter georgiopolitanum. Arch. Biochem. Biophys. 135 (1969) 45-49. [PMID: 4312076]