Reaction: pregnan-21-ol + NAD+ = pregnan-21-al + NADH + H+
Systematic name: 21-hydroxysteroid:NAD+ 21-oxidoreductase
Other name(s): 21-hydroxysteroid dehydrogenase (NAD)
Comments: Acts on a number of 21-hydroxycorticosteroids.
Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, CAS registry number: 37250-75-2
1. Monder, C. and White, A. The 21-hydroxysteroid dehydrogenases of liver. A nicotinamide adenine dinucleotide phosphate dehydrogenase and two nicotinamide adenine dinucleotide dehydrogenases. J. Biol. Chem. 240 (1965) 71-77.