IUBMB Enzyme Nomenclature

EC 1.1.1.161

Accepted name: cholestanetetraol 26-dehydrogenase

Reaction: (25R)-5β-cholestane-3α,7α,12α,26-tetraol + NAD+ = (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-al + NADH + H+

For diagram click here.

Other name(s): cholestanetetrol 26-dehydrogenase; 5β-cholestane-3α,7α,12α,26-tetrol dehydrogenase; TEHC-NAD oxidoreductase; 5β-cholestane-3α,7α,12α,26-tetraol:NAD+ 26-oxidoreductase

Systematic name: (25R)-5β-cholestane-3α,7α,12α,26-tetraol:NAD+ 26-oxidoreductase

Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 62213-60-9

References:

1. Masui, T., Herman, R. and Staple, E. The oxidation of 5β-cholestane-3α,7α,12α,26-tetraol to 5β-cholestane-3α,7α,12α-triol-26-oic acid via 5β-cholestane-3α,7α,12α-triol-26-al by rat liver. Biochim. Biophys. Acta 117 (1966) 266-268. [PMID: 5914340]

[EC 1.1.1.161 created 1976]


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