Reaction: cholest-5-ene-3β,7α-diol + NAD+ = 7α-hydroxycholest-4-en-3-one + NADH + H+
For diagram click here.
Other name(s): 3β-hydroxy-δ5-C27-steroid oxidoreductase
Systematic name: Cholest-5-ene-3β,7α-diol:NAD+ 3-oxidoreductase
Comments: Highly specific for 3β-hydroxy-C27-steroids with δ5-double bond.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 56626-16-5
1. Wikvall, K. Purification and properties of a 3β-hydroxy-δ5-C27-steroid oxidoreductase from rabbit liver microsomes. J. Biol. Chem. 256 (1981) 3376-3380. [PMID: 6937465]