IUBMB Enzyme Nomenclature

EC 1.1.1.183

Accepted name: geraniol dehydrogenase

Reaction: geraniol + NADP+ = geranial + NADPH + H+

For diagram of reaction click here.

Systematic name: geraniol:NADP+ oxidoreductase

Comments: Also acts, more slowly on farnesol but not on nerol. The enzyme produces a mixture known as citral, which includes geranial and neral. It is still not known whether neral is produced directly by the enzyme, or by isomerization of geranial.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, UM-BBD, CAS registry number: 56802-96-1

References:

1. Potty, V.H. and Bruemmer, J.H. Oxidation of geraniol by an enzyme system from orange. Phytochemistry 9 (1970) 1001-1007.

2. Sekiwa-Iijima, Y., Aizawa, Y. and Kubota, K. Geraniol dehydrogenase activity related to aroma formation in ginger (Zingiber officinale Roscoe). J. Agric. Food Chem. 49 (2001) 5902-5906. [PMID: 11743782]

3. Noge, K., Kato, M., Mori, N., Kataoka, M., Tanaka, C., Yamasue, Y., Nishida, R. and Kuwahara, Y. Geraniol dehydrogenase, the key enzyme in biosynthesis of the alarm pheromone, from the astigmatid mite Carpoglyphus lactis (Acari: Carpoglyphidae). FEBS J. 275 (2008) 2807-2817. [PMID: 18422649]

4. Saito, Y., Ito, S., Koltunow, A.M. and Sakai, H. Crystallization and preliminary X-ray analysis of geraniol dehydrogenase from Backhousia citriodora (lemon myrtle). Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 67 (2011) 665-667. [PMID: 21636906]

[EC 1.1.1.183 created 1983]


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