IUBMB Enzyme Nomenclature


Accepted name: gluconate 2-dehydrogenase

Reaction: D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+

Other name(s): 2-keto-D-gluconate reductase; 2-ketogluconate reductase

Systematic name: D-gluconate:NADP+ oxidoreductase

Comments: Also acts on L-idonate, D-galactonate and D-xylonate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 68417-42-5


1. Adachi, O., Chiyonobu, T., Shinagawa, E., Matsushita, K. and Ameyama, M. Crystalline 2-ketogluconate reductase from Acetobacter ascendens, the second instance of crystalline enzyme in genus Acetobacter. Agric. Biol. Chem. 42 (1978) 2057.

2. Chiyonobu, T., Shinagawa, E., Adachi, O. and Ameyama, M. Purification, crystallization and properties of 2-ketogluconate reductase from Acetobacter rancens. Agric. Biol. Chem. 40 (1976) 175-184.

[EC created 1989]

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