IUBMB Enzyme Nomenclature


Accepted name: 3α-hydroxyglycyrrhetinate dehydrogenase

Reaction: 3α-hydroxyglycyrrhetinate + NADP+ = 3-oxoglycyrrhetinate + NADPH + H+

Systematic name: 3α-hydroxyglycyrrhetinate:NADP+ 3-oxidoreductase

Comments: Highly specific to 3α-hydroxy derivatives of glycyrrhetinate and its analogues. Not identical to EC 3α-hydroxysteroid dehydrogenase (Si-specific).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 114308-07-5


1. Akao, T., Akao, T., Hattori, M., Namba, T. and Kobashi, K. Purification and properties of 3α-hydroxyglycyrrhetinate dehydrogenase of Clostridium innocuum from human intestine. J. Biochem. (Tokyo) 103 (1988) 504-507. [PMID: 3164718]

[EC created 1990]

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