IUBMB Enzyme Nomenclature

EC 1.1.1.237

Accepted name: hydroxyphenylpyruvate reductase

Reaction: 3-(4-hydroxyphenyl)lactate + NAD+ = 3-(4-hydroxyphenyl)pyruvate + NADH + H+

For diagram of reaction click here and another example click here.

Other name(s): HPRP

Systematic name: 4-hydroxyphenyllactate:NAD+ oxidoreductase

Comments: Also acts on 3-(3,4-dihydroxyphenyl)lactate. Involved with EC 2.3.1.140 rosmarinate synthase in the biosynthesis of rosmarinic acid.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 117590-77-9

References:

1. Petersen, M. and Alfermann, A.W. Two new enzymes of rosmarinic acid biosynthesis from cell cultures of Coleus blumei: hydroxyphenylpyruvate reductase and rosmarinic acid synthase. Z. Naturforsch. C: Biosci. 43 (1988) 501-504.

[EC 1.1.1.237 created 1992]


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