Reaction: 6-hydroxyhexanoate + NAD+ = 6-oxohexanoate + NADH + H+
Systematic name: 6-hydroxyhexanoate:NAD+ oxidoreductase
Comments: Involved in the cyclohexanol degradation pathway in Acinetobacter NCIB 9871.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, UM-BBD, CAS registry number: 77000-03-4
1. Donoghue, N.A. and Trudgill, P.W. The metabolism of cyclohexanol by Acinetobacter NCIB 9871. Eur. J. Biochem. 60 (1975) 1-7. [PMID: 1261]
2. Hecker, L.I., Tondeur, Y. and Farrelly, J.G. Formation of ε-hydroxycaproate and ε-aminocaproate from N-nitrosohexamethyleneimine: evidence that microsomal α-hydroxylation of cyclic nitrosamines may not always involve the insertion of molecular oxygen into the substrate. Chem. Biol. Interact. 49 (1984) 235-248. [PMID: 6722936]