Reaction: L-idonate + NAD(P)+ = 5-dehydro-D-gluconate + NAD(P)H + H+
Other name(s): L-idonate 5-dehydrogenase
Systematic name: L-idonate:NAD(P)+ oxidoreductase
Comments: The enzyme from the bacterium Escherichia coli is specific for 5-dehydro-D-gluconate. cf. EC 18.104.22.1686, L-idonate 5-dehydrogenase (NAD+).
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 211737-68-7
1. Bausch, C., Peekhaus, N., Utz, C., Blais, T., Murray, E., Lowary, T. and Conway, T. Sequence analysis of the GntII (subsidiary) system for gluconate metabolism reveals a novel pathway for L-idonic acid catabolism in Escherichia coli. J. Bacteriol. 180 (1998) 3704-3710. [PMID: 9658018]