IUBMB Enzyme Nomenclature


Accepted name: (R,R)-butanediol dehydrogenase

Reaction: (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H+

Other name(s): butyleneglycol dehydrogenase; D-butanediol dehydrogenase; D-(–)-butanediol dehydrogenase; butylene glycol dehydrogenase; diacetyl (acetoin) reductase; D-aminopropanol dehydrogenase; 1-amino-2-propanol dehydrogenase; 2,3-butanediol dehydrogenase; D-1-amino-2-propanol dehydrogenase; (R)-diacetyl reductase; (R)-2,3-butanediol dehydrogenase; D-1-amino-2-propanol:NAD2 oxidoreductase; 1-amino-2-propanol oxidoreductase; aminopropanol oxidoreductase

Systematic name: (R,R)-butane-2,3-diol:NAD+ oxidoreductase

Comments: Also converts diacetyl into acetoin with NADH as reductant.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, CAS registry number: 37250-09-2


1. Strecker, H.J. and Harary, I. Bacterial butylene glycol dehydrogenase and diacetyl reductase. J. Biol. Chem. 211 (1954) 263-270.

2. Taylor, M.B. and Juni, E. Stereoisomeric specificities of 2,3-butanediol dehydrogenase. Biochim. Biophys. Acta 39 (1960) 448-457.

[EC created 1961 (EC created 1972, incorporated 1976)]

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