IUBMB Enzyme Nomenclature


Accepted name: L-gulonate 3-dehydrogenase

Reaction: L-gulonate + NAD+ = 3-dehydro-L-gulonate + NADH + H+

Other name(s): L-3-aldonate dehydrogenase; L-3-aldonic dehydrogenase; L-gulonic acid dehydrogenase; L-β-hydroxyacid dehydrogenase; L-β-hydroxy-acid-NAD-oxidoreductase; L-3-hydroxyacid dehydrogenase

Systematic name: L-gulonate:NAD+ 3-oxidoreductase

Comments: Also oxidizes other L-3-hydroxyacids.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9028-51-7


1. Dworsky, P. and Hoffmann-Ostenhof, O. L-3-Aldonic acid dehydrogenase from Schwanniomyces occidentalis. Acta Biochim. Pol. 11 (1964) 269-277.

2. Smiley, J.D. and Ashwell, G. Purification and properties of β-L-hydroxy acid dehydrogenase. II. Isolation of β-keto-L-gluconic acid, an intermediate in L-xylulose biosynthesis. J. Biol. Chem. 236 (1961) 357-364.

[EC created 1961]

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