IUBMB Enzyme Nomenclature


Accepted name: hydroxypyruvate reductase

Reaction: D-glycerate + NAD(P)+ = hydroxypyruvate + NAD(P)H + H+

Other name(s): β-hydroxypyruvate reductase; NADH:hydroxypyruvate reductase; D-glycerate dehydrogenase

Systematic name: D-glycerate:NADP+ 2-oxidoreductase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9059-44-3


1. Kleczkowski, L.A. and Edwards, G.E. Identification of hydroxypyruvate and glyoxylate reductases in maize leaves. Plant Physiol. 91 (1989) 278-286.

2. Kleczkowski, L.A. and Randall, D.D. Purification and characterization of a novel NADPH(NADH)-dependent hydroxypyruvate reductase from spinach leaves. Comparison of immunological properties of leaf hydroxypyruvate reductases. Biochem. J. 250 (1988) 145-152. [PMID: 3281657]

3. Kohn, L.D. and Jakoby, W.B. Tartaric acid metabolism. VII. Crystalline hydroxypyruvate reductase (D-glycerate dehydrogenase). J. Biol. Chem. 243 (1968) 2494-2499. [PMID: 4385077]

[EC created 1972]

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