IUBMB Enzyme Nomenclature


Accepted name: cyclic alcohol dehydrogenase (quinone)

Reaction: a cyclic alcohol + a quinone = a cyclic ketone + a quinol

Other name(s): cyclic alcohol dehydrogenase; MCAD

Systematic name: cyclic alcohol:quinone oxidoreductase

Comments: This enzyme oxidizes a wide variety of cyclic alcohols. Some minor enzyme activity is found with aliphatic secondary alcohols and sugar alcohols, but not primary alcohols. The enzyme is unable to catalyse the reverse reaction of cyclic ketones or aldehydes to cyclic alcohols. This enzyme differs from EC, alcohol dehydrogenase (quinone), which shows activity with ethanol [1].

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Moonmangmee, D., Fujii, Y., Toyama, H., Theeragool, G., Lotong, N., Matsushita, K. and Adachi, O. Purification and characterization of membrane-bound quinoprotein cyclic alcohol dehydrogenase from Gluconobacter frateurii CHM 9. Biosci. Biotechnol. Biochem. 65 (2001) 2763-2772. [PMID: 11826975]

[EC created 2010]

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