Reaction: a primary alcohol + acceptor = an aldehyde + reduced acceptor
Other name(s): primary alcohol dehydrogenase; MDH; quinohemoprotein alcohol dehydrogenase; quinoprotein alcohol dehydrogenase; quinoprotein ethanol dehydrogenase; alcohol:(acceptor) oxidoreductase
Systematic name: alcohol:acceptor oxidoreductase
Comments: A quinoprotein. Acts on a wide range of primary alcohols, including methanol [cf. EC 1.1.99.20 alkan-1-ol dehydrogenase (acceptor)].
Links to other databases: BRENDA, EXPASY, KEGG, UM-BBD, PDB, CAS registry number: 37205-43-9
References:
1. Ameyama, M. and Adachi, O. Alcohol dehydrogenase from acetic acid bacteria, membrane-bound. Methods Enzymol. 89 (1982) 450-457.
2. Anthony, C. and Zatman, L.J. The microbial oxidation of methanol. Purification and properties of the alcohol dehydrogenase of Pseudomonas sp. M27. Biochem. J. 104 (1967) 953-959. [PMID: 6058112]
3. Duine, J.A., Frank, J. and Van Zeeland, J.K. Glucose dehydrogenase from Acinetobacter calcoaceticus: a 'quinoprotein'. FEBS Lett. 108 (1979) 443-446. [PMID: 520586]
4. Duine, J.A., Frank, J. and Verweil, P.E.J. Structure and activity of the prosthetic group of methanol dehydrogenase. Eur. J. Biochem. 108 (1980) 187-192. [PMID: 6250827]
5. Salisbury, S.A., Forrest, H.S., Cruse, W.B.T. and Kennard, O. A novel coenzyme from bacterial primary alcohol dehydrogenases. Nature (Lond.) 280 (1979) 843-844. [PMID: 471057]