IUBMB Enzyme Nomenclature

EC 1.11.1.13

Accepted name: manganese peroxidase

Reaction: 2 Mn(II) + 2 H+ + H2O2 = 2 Mn(III) + 2 H2O

Other name(s): peroxidase-M2; Mn-dependent (NADH-oxidizing) peroxidase

Systematic name: Mn(II):hydrogen-peroxide oxidoreductase

Comments: A hemoprotein. Involved in the oxidative degradation of lignin in white rot basidiomycetes.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, UM-BBD, CAS registry number: 114995-15-2

References:

1. Glenn, J.K., Akileswaran, L. and Gold, M.H. Mn(II) oxidation is the principal function of the extracellular Mn-peroxidase from Phanerochaete chrysosporium. Arch. Biochem. Biophys. 251 (1986) 688-696.

2. Paszczynski, A., Huynh, V.-B. and Crawford, R. Comparison of ligninase-I and peroxidase-M2 from the white-rot fungus Phanerochaete chrysosporium. Arch. Biochem. Biophys. 244 (1986) 750-765. [PMID: 3080953]

3. Wariishi, H., Akileswaran, L. and Gold, M.H. Manganese peroxidase from the basidiomycete Phanerochaete chrysosporium: spectral characterization of the oxidized states and the catalytic cycle. Biochemistry 27 (1988) 5365-5370.

[EC 1.11.1.13 created 1992]


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