Reaction: 2,3-dihydroxybenzoate + O2 = 2-carboxy-cis,cis-muconate
Other name(s): 2,3-dihydroxybenzoate 2,3-oxygenase; 2,3-dihydroxybenzoate:oxygen 2,3-oxidoreductase (decyclizing)
Systematic name: 2,3-dihydroxybenzoate:oxygen 2,3-oxidoreductase (ring-opening)
Comments: Also acts, more slowly, with 2,3-dihydroxy-4-methylbenzoate and 2,3-dihydroxy-4-isopropylbenzoate.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 56802-97-2
1. La Du, B.N. and Zannoni, V.G. The tyrosine oxidation system of liver. III. Further studies on the oxidation of p-hydroxyphenylpyruvic acid. J. Biol. Chem. 219 (1956) 273-281.
2. Sharma, H.K. and Vaidyanathan, C.S. A new mode of ring cleavage of 2,3-dihydroxybenzoic acid in Tecoma stans (L.). Partial purification and properties of 2,3-dihydroxybenzoate 2,3-oxygenase. Eur. J. Biochem. 56 (1975) 163-171. [PMID: 1175620]