IUBMB Enzyme Nomenclature


Accepted name: 3-hydroxyanthranilate 3,4-dioxygenase

Reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde

For diagram of reaction click here.

Other name(s): 3-hydroxyanthranilate oxygenase; 3-hydroxyanthranilic acid oxygenase; 3-hydroxyanthranilic oxygenase; 3-hydroxyanthranilic acid oxidase; 3HAO

Systematic name: 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)

Comments: Requires Fe2+.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, UM-BBD, CAS registry number: 9029-50-9


1. Decker, R.H., Kang, H.H., Leach, F.R. and Henderson, L.M. Purification and properties of 3-hydroxyanthranilic acid oxidase. J. Biol. Chem. 236 (1961) 3076-3082.

2. Hayaishi, O. Direct oxygenation by O2, oxygenases. In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.), The Enzymes, 2nd ed., vol. 8, Academic Press, New York, 1963, p. 353-371.

[EC created 1965 as EC, transferred 1972 to EC]

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