Reaction: protocatechuate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde
For diagram of reaction click here
Other name(s): protocatechuate 4,5-oxygenase; protocatechuic 4,5-dioxygenase; protocatechuic 4,5-oxygenase; protocatechuate:oxygen 4,5-oxidoreductase (decyclizing)
Systematic name: protocatechuate:oxygen 4,5-oxidoreductase (ring-opening)
Comments: Requires Fe2+.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, UM-BBD, CAS registry number: 9029-56-5
1. Trippett, S., Dagley, S. and Stopher, D.A. The bacterial oxidation of nicotinic acid Biochem. J. 76 (1960) 9P.