IUBMB Enzyme Nomenclature

EC 1.13.12.13

Accepted name: Oplophorus-luciferin 2-monooxygenase

Reaction: Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 +

For diagram click here.

Glossary: Oplophorus luciferin = 8-benzyl-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-3(7H)-one

Other name(s): Oplophorus luciferase

Systematic name: Oplophorus-luciferin:oxygen 2-oxidoreductase (decarboxylating)

Comments: The luciferase from the deep sea shrimp Oplophorus gracilorostris is a complex composed of more than one protein. The enzyme's specificity is quite broad, with both coelenterazine and bisdeoxycoelenterazine being good substrates.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Shimomura, O., Masugi, T., Johnson, F.H. and Haneda, Y. Properties and reaction mechanism of the bioluminescence system of the deep-sea shrimp Oplophorus gracilorostris. Biochemistry 17 (1978) 994-998. [PMID: 629957]

2. Inouye, S., Watanabe, K., Nakamura, H., Shimomura, O. Secretional luciferase of the luminous shrimp Oplophorus gracilirostris: cDNA cloning of a novel imidazopyrazinone luciferase. FEBS Lett. 481 (2000) 19-25. [PMID: 10984608]

[EC 1.13.12.13 created 2004]


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