IUBMB Enzyme Nomenclature


Accepted name: tryptophan 2-monooxygenase

Reaction: L-tryptophan + O2 = (indol-3-yl)acetamide + CO2 + H2O

Systematic name: L-tryptophan:oxygen 2-oxidoreductase (decarboxylating)

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37256-65-8


1. Kosuge, T., Heskett, M.G. and Wilson, E.E. Microbial synthesis and degradation of indole-3-acetic acid. I. The conversion of L-tryptophan to indole-3-acetamide by an enzyme system from Pseudomonas savastanoi. J. Biol. Chem. 241 (1966) 3738-3744. [PMID: 5916389]

2. Kuo, T.T. and Kosuge, T. Factors influencing the production and further metabolism of indole-3-acetic acid by Pseudomonas savastanoi. J. Gen. Appl. Microbiol. 15 (1969) 51-63.

[EC created 1972]

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