IUBMB Enzyme Nomenclature

EC 1.14.12.10

Accepted name: benzoate 1,2-dioxygenase

Reaction: benzoate + NADH + H+ + O2 = (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+

For diagram click here (another example).

Other name(s): benzoate hydroxylase; benzoate hydroxylase; benzoic hydroxylase; benzoate dioxygenase; benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, decarboxylating) [incorrect]

Systematic name: benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)

Comments: A system, containing a reductase which is an iron-sulfur flavoprotein (FAD), and an iron-sulfur oxygenase. Requires Fe2+.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, UM-BBD, CAS registry number: 9059-18-1

References:

1. Yamaguchi, M. and Fujisawa, H. Characterization of NADH-cytochrome c reductase, a component of benzoate 1,2-dioxygenase system from Pseudomonas arvilla C-1. J. Biol. Chem. 253 (1978) 8848-8853. [PMID: 214433]

2. Yamaguchi, M. and Fujisawa, H. Purification and characterization of an oxygenase component in benzoate 1,2-dioxygenase system from Pseudomonas arvilla C-1. J. Biol. Chem. 255 (1980) 5058-5063. [PMID: 7372624]

3. Yamaguchi, M. and Fujisawa, H. Subunit structure of oxygenase component in benzoate-1,2-dioxygenase system from Pseudomonas arvilla C-1. J. Biol. Chem. 257 (1982) 12497-12502. [PMID: 7130163]

[EC 1.14.12.10 created 1972 as EC 1.13.99.2, transferred 1992 to EC 1.14.12.10]


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