Reaction: benzoate + NADPH + H+ + O2 = 4-hydroxybenzoate + NADP+ + H2O
For diagram click here.
Other name(s): benzoic acid 4-hydroxylase; benzoate 4-hydroxylase; benzoic 4-hydroxylase; benzoate-p-hydroxylase; p-hydroxybenzoate hydroxylase
Systematic name: benzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)
Comments: Requires Fe2+ and tetrahydropteridine.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, UM-BBD, CAS registry number: 39391-25-8
1. Reddy, C.C. and Vaidyanathan, C.S. Purification, properties and induction of a specific benzoate-4-hydroxylase from Aspergillus niger (UBC 814). Biochim. Biophys. Acta 384 (1975) 46-57. [PMID: 236777]