IUBMB Enzyme Nomenclature


Accepted name: taxifolin 8-monooxygenase

Reaction: taxifolin + NAD(P)H + H+ + O2 = 2,3-dihydrogossypetin + NAD(P)+ + H2O

Other name(s): taxifolin hydroxylase

Systematic name: taxifolin,NAD(P)H:oxygen oxidoreductase (8-hydroxylating)

Comments: A flavoprotein, converting a flavanol into a flavanone. Also acts on fustin, but not on catechin, quercetin or mollisacidin.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 39307-19-2


1. Jeffrey, A.M., Knight, M. and Evans, W.C. The bacterial degradation of flavonoids. Hydroxylation of the A-ring of taxifolin by a soil pseudomonad. Biochem. J. 130 (1972) 373-381. [PMID: 4146277]

[EC created 1976]

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