Reaction: taxifolin + NAD(P)H + H+ + O2 = 2,3-dihydrogossypetin + NAD(P)+ + H2O
Other name(s): taxifolin hydroxylase
Systematic name: taxifolin,NAD(P)H:oxygen oxidoreductase (8-hydroxylating)
Comments: A flavoprotein, converting a flavanol into a flavanone. Also acts on fustin, but not on catechin, quercetin or mollisacidin.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 39307-19-2
1. Jeffrey, A.M., Knight, M. and Evans, W.C. The bacterial degradation of flavonoids. Hydroxylation of the A-ring of taxifolin by a soil pseudomonad. Biochem. J. 130 (1972) 373-381. [PMID: 4146277]