IUBMB Enzyme Nomenclature

EC 1.14.13.26

Accepted name: phosphatidylcholine 12-monooxygenase

Reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NADH + H+ + O2 = 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + NAD+ + H2O

Other name(s): ricinoleic acid synthase; oleate δ12-hydroxylase; oleate δ12-monooxygenase

Systematic name: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine,NADH:oxygen oxidoreductase (12-hydroxylating)

Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 77950-95-9

References:

1. Galliard, T. and Stumpf, P.K. Fat metabolism in higher plants. 30. Enzymatic synthesis of ricinoleic acid by a microsomal preparation from developing Ricinus communis seeds. J. Biol. Chem. 241 (1966) 5806-5812. [PMID: 4289003]

2. Moreau, R.A. and Stumpf, P.K. Recent studies of the enzymic-synthesis of ricinoleic acid by developing castor beans. Plant Physiol. 67 (1981) 672-676.

[EC 1.14.13.26 created 1984]


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