IUBMB Enzyme Nomenclature


Accepted name: 2-nitrophenol 2-monooxygenase

Reaction: 2-nitrophenol + NADPH + H+ + O2 = catechol + nitrite + NADP+ + H2O

Other name(s): 2-nitrophenol oxygenase; nitrophenol oxygenase

Systematic name: 2-nitrophenol,NADPH:oxygen 2-oxidoreductase (2-hydroxylating, nitrite-forming)

Comments: Involved in the metabolism of nitro-aromatic compounds by a strain of Pseudomonas putida.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, UM-BBD, CAS registry number: 104520-84-5


1. Zeyer, J., Kocher, H.P. and Timmis, N. Influence of para-substituents on the oxidative metabolism of o-nitrophenols by Pseudomonas putida B2. Appl. Environ. Microbiol. 52 (1986) 334-339. [PMID: 3752997]

[EC created 1989]

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