IUBMB Enzyme Nomenclature

EC 1.14.13.32

Accepted name: albendazole monooxygenase

Reaction: albendazole + NADPH + H+ + O2 = albendazole S-oxide + NADP+ + H2O

Other name(s): albendazole oxidase; albendazole sulfoxidase

Systematic name: albendazole,NADPH:oxygen oxidoreductase (sulfoxide-forming)

Comments: A flavoprotein (FAD).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 101299-59-6

References:

1. Fargetton, X., Galtier, P. and Delatour, P. Sulfoxidation of albendazole by a cytochrome P450-independent monooxygenase from rat liver microsomes. Vet. Res. Commun. 10 (1986) 317-324. [PMID: 3739217]

[EC 1.14.13.32 created 1989]


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