Reaction:dihydrochelirubine + NADPH + H+ + O2 = 12-hydroxydihydrochelirubine + NADP+ + H2O
For diagram click here.
Other name(s): dihydrochelirubine 12-hydroxylase
Systematic name: dihydrochelirubine,NADPH:oxygen oxidoreductase (12-hydroxylating)
Comments: a heme-thiolate protein (P-450)
Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 158736-41-5
References:
1. Kammerer, L., De-Eknamkul, W. and Zenk, M.H. Enzymic 12-hydroxylation and 12-O-methylation of dihydrochelirubine in dihydromacarpine formation by Thalictrum bulgaricum. Phytochemistry 36 (1994) 1409-1416.