IUBMB Enzyme Nomenclature


Accepted name: 4-hydroxyquinoline 3-monooxygenase

Reaction: quinolin-4-ol + NADH + H+ + O2 = quinolin-3,4-diol + NAD+ + H2O

Other name(s): quinolin-4(1H)-one 3-monooxygenase

Systematic name: quinolin-4(1H)-one,NADH:oxygen oxidoreductase (3-oxygenating)

Comments: quinolin-4-ol exists largely as the quinolin-4(1H)-one tautomer.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 144378-37-0


1. Block, D.W. and Lingens, F. Microbial metabolism of quinoline and related compounds. XIV. Purification and properties of 1H-3-hydroxy-4-oxoquinoline oxygenase, a new estradiol cleavage enzyme from Pseudomonas putida strain 33/1. Biol. Chem. Hoppe Seyler 373 (1992) 249-254. [PMID: 1627263]

[EC created 1999]

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