Reaction: 10-deoxysarpagine + NADPH + H+ + O2 = sarpagine + NADP+ + H2O
For diagram click here.
Other name(s): DOSH
Systematic name: 10-deoxysarpagine,NADPH:oxygen oxidoreductase (10-hydroxylating)
Comments: A heme-thiolate protein (P-450).
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
1. Yu, B., Ruppert, M. and Stöckigt, J. Deoxysarpagine hydroxylase a novel enzyme closing a short side pathway of alkaloid biosynthesis in Rauvolfia. Bioorg. Med. Chem. 10 (2002) 2479-2483. [PMID: 12057637]