IUBMB Enzyme Nomenclature

EC 1.14.19.2

Accepted name: acyl-[acyl-carrier-protein] desaturase

Reaction: a stearoyl-[acyl-carrier protein] + reduced acceptor + O2 = an oleoyl-[acyl-carrier protein] + acceptor + 2 H2O

Other name(s): stearyl acyl carrier protein desaturase; stearyl-ACP desaturase; acyl-[acyl-carrier-protein], hydrogen-donor:oxygen oxidoreductase

Systematic name: acyl-[acyl-carrier protein], hydrogen-donor:oxygen oxidoreductase

Comments: The enzyme from safflower is specific for stearoyl-[acyl-carrier protein]; that from Euglena acts on derivatives of a number of long-chain fatty acids. Requires ferredoxin.

Links to other databases: BRENDA, EXPASY, KEGG, PDB, CAS registry number: 37256-86-3

References:

1. Jaworski, J.G. and Stumpf, P.K. Fat metabolism in higher plants. Properties of a soluble stearyl-acyl carrier protein desaturase from maturing Carthamus tinctorius. Arch. Biochem. Biophys. 162 (1974) 158-165. [PMID: 4831331]

2. Nagai, J. and Bloch, K. Enzymatic desaturation of stearyl acyl carrier protein. J. Biol. Chem. 243 (1968) 4626-4633. [PMID: 4300868]

[EC 1.14.19.2 created 1972 as EC 1.14.99.6, modified 2000, transferred 2000 to EC 1.14.19.2]


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