Reaction: linoleoyl-CoA + AH2 + O2 = γ-linolenoyl-CoA + A + 2 H2O
Other name(s):δ6-desaturase; δ6-fatty acyl-CoA desaturase; δ6-acyl CoA desaturase; fatty acid δ6-desaturase; fatty acid 6-desaturase; linoleate desaturase; linoleic desaturase; linoleic acid desaturase; linoleoyl CoA desaturase; linoleoyl-coenzyme A desaturase; long-chain fatty acid δ6-desaturase
Systematic name: linoleoyl-CoA,hydrogen-donor:oxygen oxidoreductase
Comments: An iron protein. The rat liver enzyme is an enzyme system involving cytochrome b5 and EC 1.6.2.2, cytochrome- b5 reductase. Formerly EC 1.14.99.25.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9082-66-0
References:
1. Okayasu, T., Nagao, M., Ishibashi, T. and Imai, Y. Purification and partial characterization of linoleoyl-CoA desaturase from rat liver microsomes. Arch. Biochem. Biophys. 206 (1981) 21-28. [PMID: 7212717]