IUBMB Enzyme Nomenclature

EC 1.14.99.24

Accepted name: steroid 9α-monooxygenase

Reaction: pregna-4,9(11)-diene-3,20-dione + AH2 + O2 = 9,11α-epoxypregn-4-ene-3,20-dione + A + H2O

Other name(s): steroid 9α-hydroxylase

Systematic name: steroid,hydrogen-donor:oxygen oxidoreductase (9-epoxidizing)

Comments: An enzyme system involving a flavoprotein (FMN) and two iron-sulfur proteins.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 82869-33-8

References:

1. Strijewski, A. The steroid-9α-hydroxylation system from Nocardia species. Eur. J. Biochem. 128 (1982) 125-135. [PMID: 7173200]

[EC 1.14.99.24 created 1986]


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