Reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (Z)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O
Other name(s): n-tetradecanoyl-CoA,NADPH:O2 oxidoreductase [11-(Z) desaturating]
Systematic name: n-tetradecanoyl-CoA,NAD(P)H:O2 oxidoreductase [11-(Z) desaturating]
Comments: Involved in sex pheromone synthesis in the moth Spodoptera littoralis. (Z)-11-Tetradecenoyl-CoA is formed by stereospecific removal of H from the pro-R positions at C-11 and C-12. EC 1.14.99.31, myristoyl-CoA 11-(E) desaturase, forms the (E)-isomer by removing the pro-R H group at C-11 and the pro-S H group at C-12.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 199543-16-3
References:
1. Navaro, I., Font, I., Fabrias, G. and Camps, F. Stereospecificity of the (E)- and (Z)-11 myristoyl desaturases in the biosynthesis of Spodoptera littoralis sex pheromone. J. Am. Chem. Soc. 119 (1997) 11335-11336.