IUBMB Enzyme Nomenclature

EC 1.14.99.33

Accepted name: Δ12-fatty acid dehydrogenase

Reaction: linoleate + AH2 + O2 = crepenynate + A + 2 H2O

Glossary entries:
crepenynate: (9Z)-octadec-9-en-12-ynoate
linoleate: (9Z,12Z)-octadeca-9,12-dienoate

Other name(s): crepenynate synthase; linoleate Δ12-fatty acid acetylenase (desaturase)

Systematic name: linoleate, hydrogen-donor:oxygen oxidoreductase (Δ12-unsaturating)

Comments: Contains non-heme iron.

Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 197025-40-4

References:

1. Banas, A., Bafor, M., Wiberg, E., Lenman, M., Staahl, U. and Stymne, S. Biosynthesis of an acetylenic fatty acid in microsomal preparations from developing seeds Crepis alpina. Physiol. Biochem. Mol. Biol. Plant Lipids [Proc. Int. Symp. Plant Lipids] 12th (1997) 57-59.

2. Lee, M., Lenman, M., Banas, A., Bafor, M., Singh, S., Schweizer, M., Nilsson, R., Liljenberg, C., Dahlqvist, A., Gummeson, P.O., Sjodahl, S., Green, A. and Stymne, S. Identification of non-heme di-iron proteins that catalyze triple bond and epoxy group formation. Science 280 (1998) 915-918. [PMID: 9572738]

[EC 1.14.99.33 created 2000]


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