Reaction: α-carotene + O2 + AH2 = α-cryptoxanthin + A + H2O
For diagram of reaction click here.
Other name(s): CYP97C1; LUT1
Systematic name: α-carotene:oxygen oxidoreductase (3-hydroxylating)
Comments: A heme-thiolate protein (P450). Also acts on zeinoxanthin to give lutein.
Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number:
References:
1. Pogson, B., McDonald, K.A., Truong, M., Britton, G. and DellaPenna, D. Arabidopsis carotenoid mutants demonstrate that lutein is not essential for photosynthesis in higher plants. Plant Cell 8 (1996) 1627-1639. [PMID: 8837513]
2. Tian, L., Musetti, V., Kim, J., Magallanes-Lundback, M. and DellaPenna, D. The Arabidopsis LUT1 locus encodes a member of the cytochrome P450 family that is required for carotenoid ε-ring hydroxylation activity. Proc. Natl. Acad. Sci. USA 101 (2004) 402-407. [PMID: 14709673]