IUBMB Enzyme Nomenclature


Accepted name: succinate-semialdehyde dehydrogenase [NAD(P)+]

Reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + 2 H+

For diagram of reaction click here.

Other name(s): succinate semialdehyde dehydrogenase (nicotinamide adenine dinucleotide (phosphate)); succinate-semialdehyde dehydrogenase [NAD(P)]

Systematic name: succinate-semialdehyde:NAD(P)+ oxidoreductase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, UM-BBD, CAS registry number: 37250-88-7


1. Jakoby, W.B. Aldehyde dehydrogenase. In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 203-221.

2. Jakoby, W.B. and Scott, E.M. Aldehyde oxidation. III. Succinic semialdehyde dehydrogenase. J. Biol. Chem. 234 (1959) 937-940.

3. Nirenberg, M.W. and Jakoby, W.B. Enzymatic utilization of γ-hydroxybutyric acid. J. Biol. Chem. 235 (1960) 954-960.

[EC created 1965]

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