IUBMB Enzyme Nomenclature

EC 1.2.99.3

Accepted name: aldehyde dehydrogenase (pyrroloquinoline-quinone)

Reaction: an aldehyde + acceptor + H2O = a carboxylate + reduced acceptor

Other name(s): aldehyde dehydrogenase (acceptor)

Systematic name: aldehyde:(pyrroloquinoline-quinone) oxidoreductase

Comments: A quinoprotein. Wide specificity; acts on straight-chain aldehydes up to C10, aromatic aldehydes, glyoxylate and glyceraldehyde.

Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 75536-77-5

References:

1. Ameyama, M. and Adachi, O. Aldehyde dehydrogenase from acetic acid bacteria, membrane-bound. Methods Enzymol. 89 (1982) 491-497.

2. Ameyama, M., Osada, K., Shinagawa, E., Matsushita, K. and Adachi, O. Purification and characterization of aldehyde dehydrogenase of Acetobacter aceti. Agric. Biol. Chem. 45 (1981) 1189-1890.

3. Patel, R.N., Hou, C.T., Derelanko,P. and Felix, A. Purification and properties of a heme-containing aldehyde dehydrogenase from Methylosinus trichosporium. Arch. Biochem. Biophys. 203 (1980) 654-662. [PMID: 6779711]

[EC 1.2.99.3 created 1983, modified 1989]


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