IUBMB Enzyme Nomenclature

EC 1.20.99.1

Accepted name: arsenate reductase (donor)

Reaction: arsenite + acceptor = arsenate + reduced acceptor

For diagram of reaction click here.

Other name(s): arsenate:(acceptor) oxidoreductase

Systematic name: arsenate:acceptor oxidoreductase

Comments: Benzyl viologen can act as an acceptor. Unlike EC 1.20.4.1, arsenate reductase (glutaredoxin), reduced glutaredoxin cannot serve as a reductant.

Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 146907-46-2 (same as E 1.20.98.1)

References:

1. Krafft, T. and Macy, J.M. Purification and characterization of the respiratory arsenate reductase of Chrysiogenes arsenatis. Eur. J. Biochem. 255 (1998) 647-653. [PMID: 9738904]

2. Radabaugh, T.R. and Aposhian, H.V. Enzymatic reduction of arsenic compounds in mammalian systems: reduction of arsenate to arsenite by human liver arsenate reductase. Chem. Res. Toxicol. 13 (2000) 26-30. [PMID: 10649963]

[EC 1.20.99.1 created 2000 as EC 1.97.1.6, transferred 2001 to EC 1.20.99.1]


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