Reaction: an acyl-[acyl-carrier protein] + NADP+ = a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH + H+
Other name(s): acyl-ACP dehydrogenase; reductase, enoyl-[acyl carrier protein] (reduced nicotinamide adenine dinucleotide phosphate); NADPH 2-enoyl Co A reductase; enoyl acyl-carrier-protein reductase; enoyl-ACP reductase; enoyl-[acyl-carrier-protein] reductase (NADPH2, B-specific)
Systematic name: acyl-[acyl-carrier protein]:NADP+ oxidoreductase (B-specific)
Comments: Catalyses the reduction of enoyl-acyl-[acyl-carrier-protein] derivatives of carbon chain length from 4 to 16. The yeast and Escherichia coli enzymes are B-specific with respect to NADP+ [cf. EC 1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific)].
Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 37251-09-5
References:
1. Saito, K., Kawaguchi, A., Okuda, S., Seyama, Y. and Yamakawa, T. Incorporation of hydrogen atoms from deuterated water and stereospecifically deuterium-labeled nicotinamide nucleotides into fatty acids with the Escherichia coli fatty acid synthetase system. Biochim. Biophys. Acta 618 (1980) 202-213. [PMID: 6990992]
2. Seyama, T., Kasama, T., Yamakawa, T., Kawaguchi, A., Saito, K. and Okuda, S. Origin of hydrogen atoms in the fatty acids synthesized with yeast fatty acid synthetase. J. Biochem. (Tokyo) 82 (1977) 1325-1329. [PMID: 338601]
3. Weeks, G. and Wakil, S.J. Studies on the mechanism of fatty acid synthesis. 18. Preparation and general properties of the enoyl acyl carrier protein reductases from Escherichia coli. J. Biol. Chem. 243 (1968) 1180-1189. [PMID: 4384650]