Reaction: (S)-2-chloropropanoate + NADP+ = 2-chloroacrylate + NADPH + H+
Other name(s): CAA43 (gene name)
Systematic name: (S)-2-chloropropanoate:NADP+ oxidoreductase
Comments: The enzyme acts in the degradation pathway of unsaturated organohalogen compounds by the bacterium Burkholderia sp. WS.
Links to other databases: BRENDA, EXPASY, KEGG Metacyc, CAS registry number:
1. Kurata, A., Kurihara, T., Kamachi, H. and Esaki, N. 2-Haloacrylate reductase, a novel enzyme of the medium chain dehydrogenase/reductase superfamily that catalyzes the reduction of a carbon-carbon double bond of unsaturated organohalogen compounds. J. Biol. Chem. 280 (2005) 20286-20291. [PMID: 15781461]