EC 1.3.1.21

Reaction: cholesterol + NADP⁺ = cholesta-5,7-dien-3β-ol + NADPH + H⁺

For diagram click here.

Systematic name: cholesterol:NADP⁺ Δ⁷-oxidoreductase

Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 9080-21-1

References:

1. Dempsey, M.E., Seaton, J.D., Schroepfer, G.J. and Trockman, R.W. The intermediary role of Δ^5,7-cholestadien-3β-ol in cholesterol biosynthesis. J. Biol. Chem. 239 (1964) 1381-1387.