IUBMB Enzyme Nomenclature


Accepted name: trans-2-enoyl-CoA reductase (NADPH)

Reaction: acyl-CoA + NADP+ = trans-2,3-dehydroacyl-CoA + NADPH + H+

Other name(s): NADPH-dependent trans-2-enoyl-CoA reductase; reductase, trans-enoyl coenzyme A; trans-2-enoyl-CoA reductase (NADPH2)

Systematic name: acyl-CoA:NADP+ trans-2-oxidoreductase

Comments: Not identical with EC cis-2-enoyl-CoA reductase (NADPH) [cf. EC acyl-CoA dehydrogenase (NADP+)].

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 77649-64-0


1. Mizugaki, M., Nishimaki, T., Shiraishi, T., Kawaguchi, A., Okuda, S. and Yamanaka, H. Studies on the metabolism of unsaturated fatty acids. IX. Stereochemical studies of the reaction catalyzed by trans-2-enoyl-coenzyme A reductase of Escherichia coli. J. Biochem. (Tokyo) 92 (1982) 1649-1654. [PMID: 6759504]

[EC created 1986]

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