IUBMB Enzyme Nomenclature

EC 1.3.1.39

Accepted name: enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)

Reaction: an acyl-[acyl-carrier protein] + NADP+ = a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH + H+

Other name(s): acyl-ACP dehydrogenase; enoyl-[acyl carrier protein] (reduced nicotinamide adenine dinucleotide phosphate) reductase; NADPH 2-enoyl Co A reductase; enoyl-ACp reductase; enoyl-[acyl-carrier-protein] reductase (NADPH2, A-specific); enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific); acyl-[acyl-carrier protein]:NADP+ oxidoreductase (A-specific)

Systematic name: acyl-[acyl-carrier protein]:NADP+ oxidoreductase (Re-specific)

Comments: The liver enzyme is A-specific with respect to NADP+ [cf EC 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)].

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37251-09-5 (same number as EC 1.3.1.10)

References:

1. Dugan, R.E., Slakey, L.L. and Porter, L.W. Stereospecificity of the transfer of hydrogen from reduced nicotinamide adenine dinucleotide phosphate to the acyl chain in the dehydrogenase-catalyzed reactions of fatty acid synthesis. J. Biol. Chem. 245 (1970) 6312-6316. [PMID: 4394955]

[EC 1.3.1.39 created 1986]


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