Reaction: 2-methylbutanoyl-CoA + NAD+ = 2-methylcrotonoyl-CoA + NADH + H+
Systematic name: 2-methyl-branched-chain-acyl-CoA:NAD+ 2-oxidoreductase
Comments: A flavoprotein (FAD) from Ascaris suum. The reaction proceeds only in the presence of another flavoprotein ('electron-transferring flavoprotein').
Links to other databases: BRENDA, EXPASY, KEGG, CAS registry number: 122320-06-3
References:
1. Komuniecki, R., Fekete, S. and Thissen-Parra, J. Purification and characterization of the 2-methyl branched-chain acyl-CoA dehydrogenase, an enzyme involved in NADH-dependent enoyl-CoA reduction in anaerobic mitochondria of the nematode, Ascaris suum. J. Biol. Chem. 260 (1985) 4770-4777. [PMID: 3988734]
2. Komuniecki, R., McCrury, J., Thissen, J. and Rubin, N. Electron-transfer flavoprotein from anaerobic Ascaris suum mitochondria and its role in NADH-dependent 2-methyl branched-chain enoyl-CoA reduction. Biochim. Biophys. Acta 975 (1989) 127-131. [PMID: 2736251]