Reaction: 4-chlorobenzoyl-CoA + NADP+ + chloride = 2,4-dichlorobenzoyl-CoA + NADPH + H+
Systematic name: 4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating)
Comments: Acts in the reverse direction to form part of the 2,4-dichlorobenzoate degradation pathway in bacteria.
Links to other databases: BRENDA, EXPASY, KEGG, UM-BBD, CAS registry number:
References:
1. Romanov, V. and Hausinger, R.P. NADPH-dependent reductive ortho dehalogenation of 2,4-dichlorobenzoic acid in Corynebacterium sepedonicum KZ-4 and Coryneform bacterium strain NTB-1 via 2,4-dichlorobenzoyl coenzyme A. J. Bacteriol. 178 (1996) 2656-2661. [PMID: 8626335]