Reaction: succinate + ubiquinone = fumarate + ubiquinol
For diagram of reaction click here.
Other name(s): succinic dehydrogenase; complex II; menaquinol: fumarate oxidoreductase; fumarate reductase complex (i.e. FRD, involved in anaerobic respiration, repressed in aerobic respiration); succinate dehydrogenase complex (i. e. SDH, involved in aerobic respiration, repressed in anaerobic respiration)
Systematic name: succinate:ubiquinone oxidoreductase
Comments: A flavoprotein (FAD) containing iron-sulfur centres. The complex, present in mitochondria, can be degraded to form EC 22.214.171.124 succinate dehydrogenase, which no longer reacts with ubiquinone.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9028-11-9
1. Hatefi, Y., Ragan, C.I. and Galante, Y.M. The enzymes and the enzyme complexes of the mitochondrial oxidative phosphorylation system. In: Martonosi, A. (Ed.), The Enzymes of Biological Membranes, 2nd ed., vol. 4, Plenum Press, New York, 1985, p. 1-70.