IUBMB Enzyme Nomenclature


Accepted name: 6-hydroxynicotinate reductase

Reaction: 6-oxo-1,4,5,6-tetrahydronicotinate + oxidized ferredoxin = 6-hydroxynicotinate + reduced ferredoxin

For diagram click here.

Other name(s): 6-oxotetrahydronicotinate dehydrogenase; 6-hydroxynicotinic reductase; HNA reductase

Systematic name: 6-oxo-1,4,5,6-tetrahydronicotinate:ferredoxin oxidoreductase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9030-84-6


1. Holcenberg, J.S. and Tsai, L. Nicotinic acid metabolism. IV. Ferredoxin-dependent reduction of 6-hydroxynicotinic acid to 6-oxo-1,4,5,6-tetrahydronicotinic acid. J. Biol. Chem. 244 (1969) 1204-1211. [PMID: 5767303]

[EC created 1972]

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