IUBMB Enzyme Nomenclature

EC 1.3.99.1

Accepted name: succinate dehydrogenase

Reaction: succinate + acceptor = fumarate + reduced acceptor

Other name(s): succinic dehydrogenase; fumarate reductase; fumaric hydrogenase; succinodehydrogenase; succinic acid dehydrogenase; succinate oxidoreductase; succinyl dehydrogenase; succinate:(acceptor) oxidoreductase

Systematic name: succinate:acceptor oxidoreductase

Comments: A flavoprotein (FAD) containing iron-sulfur centres. A component of EC 1.3.5.1 succinate dehydrogenase (ubiquinone).

Links to other databases: BRENDA, EXPASY, GTD, KEGG, PDB, CAS registry number: 9002-02-2

References:

1. Hatefi, Y., Ragan, C.I. and Galante, Y.M. The enzymes and the enzyme complexes of the mitochondrial oxidative phosphorylation system. In: Martonosi, A. (Ed.), The Enzymes of Biological Membranes, 2nd ed., vol. 4, Wiley, New York, 1985, p. 1-70.

2. Singer, T.P. and Kearney, E.B. Succinate dehydrogenase. In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 383-445.

3. Singer, T.P., Kearney, E.B. and Bernath, P. Studies of succinic dehydrogenase. II. Isolation and properties of the dehydrogenase from beef heart. J. Biol. Chem. 223 (1956) 599-613.

4. Warringa, M.G.P.J. and Giuditta, A. Studies on succinic dehydrogenase. IX. Characterization of the enzyme from Micrococcus lactilyticus. J. Biol. Chem. 230 (1958) 111-123.

[EC 1.3.99.1 created 1961]


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